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2021 Impact Factor 1.766
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Korean Journal of Biological Psychiatry 1998;5(2):210-14. Published online: Feb, 1, 1998
An association study with Korean schizophrenic patients(N=84) and normal controls(N=87) was performed to find the relationship between catechol-Ο-methyltransferase(COMT) gene polymorphism and schizophrenia using polymerase chain reaction-restriction fragment length polymorphism. When we compared the allele and genotype frequencies of BglI COMT gene polymorphism in schizophrenics and normal controls, there was no significant difference between two groups. Our results do not support an association between the BglI polymorphism of COMT gene and schizophrenia.
Keywords Schizophrenia;Association;COMT;Polymorphism;Alleles.