Oct, 1, 2023

Vol.30 No.2, pp. 84-88


Review

  • Korean Journal of Biological Psychiatry
  • Volume 2(2); 1995
  • Article

Review

Korean Journal of Biological Psychiatry 1995;2(2):205-17. Published online: Feb, 1, 1995

The Pharmacology and the Clinical Use of Selective Serotonin Reuptake Inhibitors

  • Min-Soo Lee, MD1; and Pyo-Han Kim, MD2;
    1;Department of Neuropsychiatry, Korea University College of Medicine, Seoul, 2;Department of Neuropsychiatry, Seoul Adventist Hospital, Seoul, Korea
Abstract

In comparison with tricyclic antidepressants(TCAs), one of the most interesting characteristics of selective serotinin reuptake inhibitors(SSRIs) is its structural differences, reveals differences, reveals different pharmacological properties. The applications at the moment are most effective in clinical applications to deression. The limited result of the research to date on the various applications of SSRIs has not revealed the total potential and applicability of SSRIs. Therefore, attending phycicians utilizing SSRIs do not know the full capabilities of the drug on patients and what the patients may reap in terms of benefit from its curing elements. Physicians must first try to understand the full potential of SSRIs and its potential applications for it to be effective on patients, recently, it has been determined that SSRIs and other drugs when administered together may be more effective in the healing process because SSRIs complements and aids in the enhancement and effect of the other drugs. This article is written to give attention to the reader of the pharmacological properties and the clinical use of SSRIs. It is the authors's hope that continuous research on the porticular aspects of SSRIs can aid the clinicians in the use of this SSRIs.

Keywords SSRIs;Pharmacodynamics;Pharmacokinetics;Drug interactions;Clinical use.