Oct, 1, 2023

Vol.30 No.2, pp. 84-88

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Review

  • Korean Journal of Biological Psychiatry
  • Volume 14(1); 2007
  • Article

Review

Korean Journal of Biological Psychiatry 2007;14(1):48-54. Published online: Jan, 1, 2007

Abstract PDF Full Text

Relationship between Behavioral and Psychological Symptoms and Patient and Caregiver Quality of Life in Alzheimer's Disease

  • Sung-Wan Kim, MD, PhD1,2,3; and Il-Seon Shin, MD, PhD1,2,3;
    1;Clinical Trial Center, Chonnam National University Hospital, Gwangju, 2;Department of Psychiatry, Chonnam National University Medical School, Gwangju, 3;Department of Psychiatry, Hwasun Chonnam National University Hospital, Hwasun, Korea
Abstract

Objectives：This study aimed to examine the relationship between behavioral and psychological symptoms of dementia(BPSD) and patient and caregiver QOL in Alzheimer’s disease(AD).

Methods：Fifty-one AD patients and their caregivers participated. Measures about patients were Neuropsychiatric Inventory(NPI), Korean version of QOL-Alzheimer’s Disease(KQOL-AD), Activities of Daily Living(ADL), Clinical Dementia Rating(CDR), and Korean version-Mini Mental State Examination(K-MMSE). Caregiver QOL was assessed with KQOL-AD and General Health Questionnaire/Quality of Life-12(GHQ/ QOL-12).

Results：Patient QOL-AD on patient ratings was negatively correlated with appetite/eating change and NPI scores. Patient QOL-AD on caregiver ratings was negatively correlated with hallucinations, depression/dysphoria, and NPI scores. Caregiver QOL assessed by the GHQ/QOL-12 was negatively correlated with agitation/aggression, depression/dysphoria, and NPI scores and was negatively correlated with distress related to agitation/aggression, depression/dysphoria, and NPI scores.

Conclusion：BPSD of AD patients was associated with low QOL of both patients and caregivers. Thus, interventions of BPSD were needed to improve both patient and caregiver QOL.

Keywords Alzheimer’s disease;Behavioral and psychological symptoms;Quality of life;Caregiver.