Oct, 1, 2023

Vol.30 No.2, pp. 84-88

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Review

  • Korean Journal of Biological Psychiatry
  • Volume 20(2); 2013
  • Article

Review

Korean Journal of Biological Psychiatry 2013;20(2):29-30. Published online: Feb, 1, 2013

Abstract PDF Full Text

Ketamine as a Rapid-Acting Antidepressant

  • Daeyoung Oh, MD
    Department of Neuropsychiatry, Hanyang University College of Medicine, Guri Hospital, Guri, Korea
Abstract

First-line therapy of depression is a pharmacological treatment. Many prescribed antidepressants modulate monoamine neurotransmitters including serotonin, norepinephrine and dopamine. Recently, Ketamine, an N-methyl-D-aspartate receptor antagonist, has received attention and has been investigated for clinical trials and neurobiological studies. Here, I introduce ketamine as a rapid-acting antidepressant.

Keywords Depression;NMDA;Ketamine;mTOR.