Oct, 1, 2023

Vol.30 No.2, pp. 84-88


Review

  • Korean Journal of Biological Psychiatry
  • Volume 5(1); 1998
  • Article

Review

Korean Journal of Biological Psychiatry 1998;5(1):107-13. Published online: Jan, 1, 1998

The Relation of Onset-Age and β-Endorphin Levels in Alcohol Dependence

  • Hee-Yeon Jeong, MD1;In-Joon Park, MD1;in-Man Kim, MD1; and Hyuk-Hee Jin, MD2;
    1;Department of Psychiatry, College of Medicine, Soonchunhyang University, Chun-an, 2;Department of Psychiatry, College of Medicine, Soonchunhyang University, Ku-mi, Korea
Abstract

Objectives:To evaluate the relation of onset-age and plasma level of β-endorphin, Ethanol, β-endorphin, cortisol and blood glucose were compared in 48 male alcoholics and 29 normal controls

Methods:Alcoholics are divided into two groups by onset-age of alcoholism. Blood samples were obtained before and after 0.75gm/kg of ethanol consumption at the 7th admission day.

Results:
1) The ratio of onset-age before 25 years to after 25 years of the patient group was 2 to 3. 2) There was no significant difference in age at admission between two patient groups. 3) There was no significant difference in change of plasma ethanol levels among three groups. 4) There was no significant difference in change of plasma β-endorphin levels among three groups. 5) There was no significant difference in change of plasma cortisol level among three groups. 6) There was no significant difference in change of fasting blood sugar level among two patient groups.

Keywords Alcoholism;Onset-age;β-Endorphin.