Oct, 1, 2023

Vol.30 No.2, pp. 84-88

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Review

  • Korean Journal of Biological Psychiatry
  • Volume 5(1); 1998
  • Article

Review

Korean Journal of Biological Psychiatry 1998;5(1):134-7. Published online: Jan, 1, 1998

Abstract PDF Full Text

A Case of Antipsychotic-Regression Syndrome in Haloperidol Treated Tourette’s Syndrome

  • Hee-yeon Jeong, MD1;Hyun-Ju Cho, MA1;Young-Joon Kwon, MD1;In-Joon Park, MD1;and Hyuk-Hee Jin, MD2;
    1;Department of Neuropsychiatry, College of Medicine, Soonchunhyang University, Chun-an, 2;Department of Neuropsychiatry, College of Medicine, Soonchunhyang University, Ku-mi, Korea
Abstract

Authors report a case of separation anxiety disorder, which developed as a side effect during haloperidol treatment of Tourette syndrome(TS). In this case, 14 years old boy developed attention deficit symptoms during his infancy. At 4th grade of primary school, he developed vocal tic, motor tic, and coprolalia. With 5mg/day of haloperidol treatment his symptoms of TS were subsided. During the treatment, he developed features of separation anxiety disorder, including dependence, pleading, clinging, and sadness. Symptoms of attention deficit and separation anxiety disorder were improved by 25mg/day of imipramine treatment. During haloperidol treatment of TS, careful observation may be needed whether separation anxiety disorder-like symptom develops.

Keywords Tourette syndrome;Separation anxiety disorder;Haloperidol;Imipramine.