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Korean Journal of Biological Psychiatry 1998;5(2):248-52. Published online: Feb, 1, 1998
Object:This study was performed in order to examine the correlation between acute neuroleptic-induced dystonic reactions and serum iron level.
Method:Serum iron levels were measured in psychiatric inpatients who had developed acute neuroleptic-induced dystonia(N=41) and in control patients with no history of acute dystonic reactions(N=37). Serum iron levels were compared in acute dystonic inpatients before starting treatment with neuroleptics and after acute dystonic reaction.
Results:The patients exhibiting acute dystonic reactions had significantly lower serum iron levels than the patients without acute dystonic reactions.
Conclusion:This result supports an association between low serum iron and the occurrence of neuroleptic-induced acute dystonic reactions.
Keywords Serum iron;Acute dystonic reactions;Antipsychotic drug.