Oct, 1, 2023

Vol.30 No.2, pp. 84-88

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  • Korean Journal of Biological Psychiatry
  • Volume 5(2); 1998
  • Article

Review

Korean Journal of Biological Psychiatry 1998;5(2):248-52. Published online: Feb, 1, 1998

Abstract PDF Full Text

The Relation of Antipsychotic Drug Induced-Acute Dystonia and Serum Iron Level

  • Dong-Jin Lee, MD1;In-Joon Park, MD1;Young-Joon Kwon, MD1;Hee-Yeon Jeong, MD1;and Sun-Ho Han, MD2;
    1;Department of Psychiatry, College of Medicine, Soonchunhyang University, Chun-an, 2;Department of Psychiatry, College of Medicine, Soonchunhyang University, Seoul, Korea
Abstract

Object：This study was performed in order to examine the correlation between acute neuroleptic-induced dystonic reactions and serum iron level.

Method：Serum iron levels were measured in psychiatric inpatients who had developed acute neuroleptic-induced dystonia(N＝41) and in control patients with no history of acute dystonic reactions(N＝37). Serum iron levels were compared in acute dystonic inpatients before starting treatment with neuroleptics and after acute dystonic reaction.

Results：The patients exhibiting acute dystonic reactions had significantly lower serum iron levels than the patients without acute dystonic reactions.

Conclusion：This result supports an association between low serum iron and the occurrence of neuroleptic-induced acute dystonic reactions.

Keywords Serum iron;Acute dystonic reactions;Antipsychotic drug.