Oct, 1, 2023

Vol.30 No.2, pp. 84-88


Review

  • Korean Journal of Biological Psychiatry
  • Volume 6(2); 1999
  • Article

Review

Korean Journal of Biological Psychiatry 1999;6(2):235-9. Published online: Feb, 1, 1999

The Effects of Estrogen Replacement Therapy on Depressive Symptoms and Attention in Postmenopaual Women

  • Baik Seok Lee, MD, PhD1;Sung Yeop Kim, MD1;Sang Hoon Lee, MD, PhD2;Bum Woo Nam, MD1;and Kyung Joon Min, MD1;
    1;Department of Neuropsychiatry, 2;Obstetrics and Gynecology, College of Medicine, Chung-Ang University, Seoul, Korea
Abstract

Objectives:The purpose of this study was to evaluate the difference of depressive symptoms and attention between estrogen user and non-user in postmenopausal women.

Methods:30 Estrogen users and 30 non-users were participated in this study. They were all menopausal for at least 1 year and have 12 or more education years. We used BDI(Beck depression inventory), digit span and digit symbol to evaluate depressive symptoms and attention in both groups. WWe also measured the plasmaestradiol level and identified the correlation between estradiol level and BDI, digit span and digit symbol.

Results:The demographic data was not different between both groups. Estrogen users scored higher than non-users in digit span(forward) and lower than non-users in BDI. The correlation between estradiol level and BDI, digit span and digit symbol was not significant.

Conclusion:Estrogen replacement therapy was effective in alleviating depressive symptoms but ineffective in improving attention in postmenopausal women.

Keywords Postmenopausal women;Estrogen;Depression;Attention.