Oct, 1, 2023

Vol.30 No.2, pp. 84-88

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Review

  • Korean Journal of Biological Psychiatry
  • Volume 9(1); 2002
  • Article

Review

Korean Journal of Biological Psychiatry 2002;9(1):3-7. Published online: Jan, 1, 2002

Abstract PDF Full Text

Serotonin(2A) Receptor Gene Promoter Polymorphism in Mood Disorder and Mood-Related Disorders

  • Ik-Seung Chee, MD
    Department of Psychiatry, College of Medicine, Chungnam National University, Daejon, Korea
Abstract

Genes involved in the serotonin system are good candidates for the pathogenesis of mood disorder and mood-related disorders, such as eating disorder, obsessive-compulsive disorder, alcoholism, and suicide. Serotonin type 2A(5-HT2A) receptor gene promoter polymorphism(-1438A/G) has been reported. In this article, authors reviewed the literatures regarding association studies between -1438A/G and mood disorder and mood-related disorders. There are controversial results with limited data to date. Further researches on the -1438A/G in psychiatric disorders are required.

Keywords Mood disorders;5-HT2A receptor gene promoter;Polymorphism;-1438A/G.